Cambridge, England, September 11-14, 2011
Monday, 12. September 2011
12:15 - 14:00
- Cardiovascular and Myocardial Physiology and Disease
- Pharmacology of Endothelin Receptors and Antagonists
- Results from New Clinical Studies
Potential role of ET-1 in ischaemic muscle damage
Hemanshu Patel, Xu Shiwen, Michael Dashwood, Daryll Baker, Janice Tsui
γ-Aminobutyric acid attenuates monocrotaline-induced pulmonary hypertension by suppressing sympathetic nervous system but not cardiac ET-1 system
Rie Suzuki, Mamoru Ohkita, Yasuo Matsumura
Potentiating Bradykinin Pathway by Genetic Suppression of Endothelin-converting Enzyme-1 Prevented Hypoxic induced Pulmonary Hypertension and Right Ventricular Hypertrophy.
Yoko Suzuki, Sunu Budhi Raharjo, Nakayama Kazuhiko, Nicolas Vignon, Susi Heiden, Nur Arfian, Anggoro Budi Hart Opo, Keiko Yagi, Noriaki Emoto
Endothelin-1 and calcitonin gene-related peptide are both involved in hypertension; evidence from 2 experimental models of hypertension
Jelly Nelissen, Bart Heijnen, Pieter Lemkens, Merlijn Meens, Jacques Debets, Helma van Essen, Jet Bost, Paul Schiffers, Harry Struijker-Boudier, Jo De Mey, Ben Janssen
Myocardial ischemia-reperfusion induces upregulation of contractile endothelin ETB receptor in rat coronary arteries
Gry Freja Skovsted, Majid Sheykhzade, Simon Trautner, Lars Edvinsson
Endothelial Cell-Derived Endothelin-1 Promotes Cardiac Lipid Accumulation in Diabetic Heart
Bambang Widyantoro, Noriaki Emoto, Takashi Suzuki, Masashi Yanagisawa, Ken-ichi Hirata
Ambrisentan and tadalafil synergistically relax endothelin-induced contraction of rat pulmonary arteries
Faquan Liang, Suya Yang, Luiz Belardinelli, John Shryock
Does biased agonism explain the discrepant pharmacology of ET-1 and S6b?
Janet Maguire, Rhoda Kuc, Lowell Ling, Anthony Davenport
Selective ETA receptor antagonism attenuates neointimal lesion development in the mouse femoral artery
Karolina Duthie, Eileen Miller, Jessica Ivy, John McShane, David Webb, Patrick Hadoke
Differential effects of Raf inhibitors on upregulation of contractile endothelin B receptors in rat cerebral arteries after organ culture
Hilda Ahnstedt, Lars Edvinsson
Charachterisation of endothelin receptor sub-types in pulmonary endarterectomy (PEA) specimens from patients with chronic thromboembolic pulmonary hypertension (CTEPH)
Rhoda Kuc, Lowell Ling, Janet Maguire, Mark Southwood, Russell MacKenzie Ross, Guy Hagan, Ellen Moseley, Karen Sheares, David Jenkins, Martin Goddard, Joanna Pepke-Zaba, Anthony Davenport
Plasma endothelin and big endothelin levels in cardiovascular subjects and effects of Bosentan
Yumi Miyauchi, Seiji Maeda, Satoshi Sakai, Jun Sugawara, Nobutake Shimojoh, Subrina Jesmin, Shigeyuki Watanabe, Satoshi Homma, Kazutaka Aonuma, Takashi Miyauchi
ET-1 plasma level and vascular endothelial dysfunction in primary open angle glaucoma
Mauro Cellini, Ernesto Strobbe, Corrado Gizzi, Nicole Balducci, Pier Giorgio Toschi, Emilio Campos
Endothelin receptors in normal and cirrhotic human liver
Lowell Ling, Rhoda Kuc, Janet Maguire, Neil Davie, Paul Gibbs, Graeme Alexander, Anthony Davenport
What is the best method of proteinuria measurement in clinical trials of antiproteinuric drugs?
Jonathan Towler, Neeraj Dhaun, Iain MacIntyre, Jane Goddard, David Webb
Pharmacokinetic and pharmacodynamic properties of SOL1 a novel dual neutral endopeptidase (NEP) / endothelin converting enzyme (ECE) inhibitor in rats
B. Janssen, H. Sann, J. Nelissen, D. Jasserand, J. De Mey
Calcium channels and CAMK involvement in endothelin receptors expression
Roya Waldsee, Hilda Ahnstedt, Sajedeh Eftekhari, Lars Edvinsson
Different pharmacology of ETA and ETB receptors revealed in β-arrestin assay
Janet Maguire, Rhoda Kuc, Andrew Green, Mike Brown, Sanj Kumar, Tom Wehrman, Elizabeth Quinn, Anthony Davenport
Structure-activity relationship of Endothelin-1 and Endothelin-2, revisited. isolated rat mesenteric resistance arteries
Compeer MG, de Lange JA, Meens MJPMT, Hackeng TM, Nicolaes G, De Mey JGR
Tie1-dependent endothelial cell-restricted over-expression of endothelin-1 impairs contractions to serotonin in the mouse aorta
François YL Li, Oliver Baretella, Eva HC Tang, Karen SL Lam, Sookja K Chung, Paul M Vanhoutte, Aimin Xu